FACTOR V

Factor V / Proaccelerin / Labile factor deficiency is an inherited autosomal recessive disorder which is usually asymptomatic. Homozygous Factor V deficiency is rare, leading to easy bruising & mucosal bleeding in children. Patients with Factor V deficiency should also perform Factor VIII assays to evaluate for combined deficiency. Acquired deficiencies may be seen in liver disease and Disseminated Intravascular Coagulation.