FACTOR V (Leiden activity)

Factor V / Proaccelerin / Labile factor deficiency is an inherited autosomal recessive disorder which is usually
asymptomatic. Homozygous Factor V deficiency is rare, leading to easy bruising & mucosal bleeding in
children. Patients with Factor V deficiency should also perform Factor VIII assays to evaluate for combined
deficiency. Acquired deficiencies may be seen in liver disease and Disseminated Intravascular Coagulation.